Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 8/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132037 | 0.84 | STS (0.49) | STSHSD17B1LMNAMAPTRECQL | |
| SCHEMBL7060058 | 0.81 | STS (0.50) | STSHSD17B1LMNAMAPTRECQL | |
| SCHEMBL1656763 | 0.81 | STS (0.50) | STSHSD17B1LMNAMAPTRECQL | |
| SCHEMBL6569494 | 0.75 | ESR1 (0.40) | STSLMNAESR1ESR2CYP3A4 | |
| SCHEMBL8409267 | 0.75 | STS (0.51) | STSHSD17B1LMNAMAPTRECQL | |
| SCHEMBL1659350 | 0.73 | STS (0.49) | STSHSD17B1LMNAMAPTRECQL | |
| SCHEMBL1236173 | 0.73 | STS (0.49) | STSHSD17B1LMNAMAPTRECQL | |
| SCHEMBL5155997 | 0.73 | SRD5A2 (0.39) | STSLMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL12888961 | 0.73 | STS (0.49) | STSHSD17B1LMNAMAPTRECQL | |
| SCHEMBL1236171 | 0.73 | STS (0.49) | STSHSD17B1LMNAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1310509-A2 | Novel anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use | Sri International (US) | 2003-05-14 | — | — | EP | disclosed |