SCHEMBL7060126

SCHEMBL7060126

CCCCCCCCCCCCCCCCCC(=O)O[SiH](C)OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.52
LMNA P02545 2/20 0.48
DNM1 Q05193 1/20 0.47
PAM P19021 2/20 0.47
MAPT P10636 2/20 0.46
MAPK1 P28482 1/20 0.46
CES2 O00748 3/20 0.45
CES1 P23141 3/20 0.45
TSHR P16473 4/20 0.44
PPARG P37231 5/20 0.43
PPARD Q03181 5/20 0.43
PPARA Q07869 5/20 0.43
HDAC11 Q96DB2 4/20 0.43
GPR84 Q9NQS5 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TLR2 O60603 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
FABP4 P15090 2/20 0.43
PTPN1 P18031 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7058908 1.00 DGKA (0.52) DGKALMNADNM1PAMMAPT
SCHEMBL7060608 0.83 DGKA (0.50) DGKALMNADNM1PAMMAPT
SCHEMBL7051612 0.83 DGKA (0.50) DGKALMNADNM1PAMMAPT
SCHEMBL28063153 0.82 DGKA (0.53) DGKALMNAPAMMAPTMAPK1
SCHEMBL28063152 0.82 DGKA (0.53) DGKALMNAPAMMAPTMAPK1
SCHEMBL7057700 0.82 DGKA (0.57) DGKALMNAPAMMAPTMAPK1
SCHEMBL14312808 0.82 DGKA (0.57) DGKALMNAPAMMAPTMAPK1
SCHEMBL14312289 0.82 DGKA (0.57) DGKALMNAPAMMAPTMAPK1
SCHEMBL7055137 0.82 DGKA (0.57) DGKALMNAPAMMAPTMAPK1
SCHEMBL14312561 0.82 DGKA (0.57) DGKALMNAPAMMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006118-B1 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond DOW CORNING ASIA LTD (JP) 2003-05-07 EP disclosed
EP-1085022-A1 A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds Dow Corning Asia, Ltd. (JP) 2001-03-21 EP disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-6111126-A Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond DOW CORNING ASIA, LTD. (JP) 2000-08-29 US disclosed
EP-1006118-A2 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond Dow Corning Asia, Ltd. (JP) 2000-06-07 EP disclosed
US-6060620-A Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds DOW CORNING ASIA, LTD. (JP) 2000-05-09 US disclosed