SCHEMBL7060628

SCHEMBL7060628

CCCC(=O)OC(=O)CCC.CCCC(=O)OC(=O)CCC.CCCCC(=O)OC(=O)CCCC

nearest known ligand 0.79

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.79
CES1 P23141 4/20 0.50
CES2 O00748 3/20 0.50
DGKA P23743 1/20 0.48
TP53 P04637 1/20 0.46
LMNA P02545 2/20 0.45
CA1 P00915 1/20 0.44
PAM P19021 2/20 0.43
NAAA Q02083 1/20 0.43
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL871384 1.00 ALDH1A1 (0.79) ALDH1A1CES1CES2DGKATP53
SCHEMBL7060626 1.00 ALDH1A1 (0.79) ALDH1A1CES1CES2DGKATP53
SCHEMBL242588 0.95 ALDH1A1 (0.68) ALDH1A1CES1CES2DGKATP53
Trimethylammonium SCHEMBL3410273 0.93 ALDH1A1 (0.68) ALDH1A1CES1CES2DGKATP53
SCHEMBL4631123 0.92 ALDH1A1 (0.75) ALDH1A1CES1CES2DGKALMNA
SCHEMBL27467140 0.92 ALDH1A1 (0.65) ALDH1A1CES1CES2DGKATP53
Fluoride SCHEMBL28138819 0.92 ALDH1A1 (0.65) ALDH1A1CES1CES2DGKATP53
SCHEMBL195017 0.92 ALDH1A1 (0.83) ALDH1A1CES1CES2DGKALMNA
SCHEMBL1425972 0.90 ALDH1A1 (0.71) ALDH1A1CES1CES2DGKALMNA
SCHEMBL15527920 0.90 ALDH1A1 (0.71) ALDH1A1CES1CES2DGKALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0866798-B1 PREPARATION OF ESTER DERIVATIVES OF STEROIDS POPULATION COUNCIL INC (US) 2003-05-14 EP disclosed
EP-0866798-A4 PREPARATION OF ESTER DERIVATIVES OF STEROIDS POPULATION COUNCIL INC (US) 1998-12-02 EP disclosed
EP-0866798-A1 PREPARATION OF ESTER DERIVATIVES OF STEROIDS THE POPULATION COUNCIL, INC. (US) 1998-09-30 EP disclosed
US-5710293-A ACYLATION OF A NORPROGESTERONE WITH ANHYDRIDE OR ACYL HALIDE, CATALYZED BY PERCHLORIC ACID THE POPULATION COUNCIL, CENTER FOR BIOMEDICAL RESEARCH (US) 1998-01-20 US disclosed
WO-1997013779-A1 PREPARATION OF ESTER DERIVATIVES OF STEROIDS THE POPULATION COUNCIL, INC. (US) 1997-04-17 WO disclosed