Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260408 | 0.89 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL17923899 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3651832 | 0.86 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3884348 | 0.84 | SMPD1 (0.30) | — | |
| SCHEMBL3883028 | 0.84 | SMPD1 (0.30) | — | |
| SCHEMBL11865816 | 0.81 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2321002 | 0.81 | SMPD1 (0.30) | — | |
| SCHEMBL176508 | 0.80 | THRB (0.38) | TSHRALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL2321681 | 0.78 | TDP1 (0.34) | — | |
| Allylamine SCHEMBL28314014 | 0.78 | THRB (0.33) | TSHRTHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105517585-B | Bioactivity coatings | 生物相互作用有限公司 | 2019-11-22 | — | — | CN | claimed |
| CN-104678462-B | Silicone hydrogel lens with crosslinking hydrophilic coating | 诺华股份有限公司 | 2019-11-05 | — | — | CN | claimed |
| CN-110051886-A | The medical device and method that antithrombotic generates | 柯惠有限合伙公司 | 2019-07-26 | — | — | CN | claimed |
| CN-108710221-A | Ophthalmic lens and method for producing same | 明基材料股份有限公司 | 2018-10-26 | — | — | CN | claimed |
| CN-103910900-B | Surface modifying method and the elastomer of surface modification | 住友橡胶工业株式会社 | 2017-03-01 | — | — | CN | claimed |
| CN-106456834-A | Prosthesis for in vivo insertion, coated with cross-linked polyphosphorylcholine | 首尔大学校产学协力团 | 2017-02-22 | — | — | CN | claimed |
| CN-114437128-A | Choline phosphate modified paclitaxel medicine and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2022-05-06 | — | — | CN | disclosed |
| CN-104678462-B | Silicone hydrogel lens with crosslinking hydrophilic coating | 诺华股份有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-110114856-A | Rinse agent composition for silicon wafer | 花王株式会社 | 2019-08-09 | — | — | CN | disclosed |
| CN-109312246-A | Slip imparting agent and slip adding method | 日油株式会社 | 2019-02-05 | — | — | CN | disclosed |
| CN-105334640-B | Silicone hydrogel lenses with rich water surface | 诺华股份有限公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-108948282-A | Water-soluble silicon high polymer, silicon hydrogel composition, silicon hydrogel lens and manufacturing method | 晶硕光学股份有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-107661235-A | Oil type cosmetic in water | 富士胶片株式会社 | 2018-02-06 | — | — | CN | disclosed |
| CN-106474568-A | Surface modification of metals and the method for modifying of metal surface | 住友橡胶工业株式会社 | 2017-03-08 | — | — | CN | disclosed |
| CN-106456834-A | Prosthesis for in vivo insertion, coated with cross-linked polyphosphorylcholine | 首尔大学校产学协力团 | 2017-02-22 | — | — | CN | disclosed |
| CN-106397822-A | SURFACE MODIFICATION METHOD AND SURFACE-MODIFIED BODY | 住友橡胶工业株式会社 | 2017-02-15 | — | — | CN | disclosed |
| CN-104349744-B | Sliding member and method for manufacturing same | 京瓷医疗株式会社 | 2016-09-07 | — | — | CN | disclosed |
| EP-0823458-B1 | POLYMERIC MATERIAL, MEDICAL MATERIAL AND LIQUID POLYMER COMPOSITION | NOF CORP (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-5977257-A | Polymer material, medical material and liquid high molecular composition | NOF CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0823458-A1 | POLYMERIC MATERIAL, MEDICAL MATERIAL AND LIQUID POLYMER COMPOSITION | NOF CORPORATION (JP) | 1998-02-11 | — | — | EP | disclosed |