Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bromoxynil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.83 |
| ▸ | ALB | P02768 | 2/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromoxynil SCHEMBL9863697 | 0.92 | TTR (0.76) | TTRALBMEN1KMT2ATSHR | |
| Bromoxynil SCHEMBL1701902 | 0.91 | TTR (1.00) | TTRALBMEN1KMT2ATSHR | |
| Bromoxynil SCHEMBL19210 | 0.91 | TTR (1.00) | TTRALBMEN1KMT2ATSHR | |
| Bromoxynil SCHEMBL22721314 | 0.89 | TTR (0.95) | TTRALBMEN1KMT2ATSHR | |
| Bromoxynil SCHEMBL29642876 | 0.89 | TTR (0.95) | TTRALBMEN1KMT2ATSHR | |
| Bromoxynil SCHEMBL466353 | 0.89 | TTR (0.95) | TTRALBMEN1KMT2ATSHR | |
| Bromoxynil SCHEMBL726301 | 0.89 | TTR (0.95) | TTRALBMEN1KMT2ATSHR | |
| Bromoxynil SCHEMBL3300254 | 0.82 | TTR (0.61) | TTRALBMEN1KMT2ATSHR | |
| Bromoxynil SCHEMBL5148039 | 0.82 | TTR (0.73) | TTRALBMEN1KMT2ATSHR | |
| SCHEMBL20906090 | 0.80 | TTR (0.78) | TTRALBMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759371-B2 | INCORPORATING ALKOXYLATED FATTY ACID ESTER EMULSIFIER | COGNIS DEUTSCHLAND GMBH & CO. KG (DE) | 2004-07-06 | — | — | US | claimed |