Bromoxynil

Bromoxynil

SCHEMBL1701902

N#Cc1cc(Br)c(O)c(Br)c1.N#Cc1cc(Br)c(O)c(Br)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 1.00
ALB P02768 2/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
HTT P42858 1/20 0.43
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
RECQL P46063 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA2 P00918 2/20 0.40
CA6 P23280 2/20 0.40
CA1 P00915 1/20 0.40
CA4 P22748 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromoxynil SCHEMBL19210 1.00 TTR (1.00) TTRALBMEN1KMT2ACYP3A4
Bromoxynil SCHEMBL726301 0.97 TTR (0.95) TTRALBMEN1KMT2ACYP3A4
Bromoxynil SCHEMBL22721314 0.97 TTR (0.95) TTRALBMEN1KMT2ACYP3A4
Bromoxynil SCHEMBL29642876 0.97 TTR (0.95) TTRALBMEN1KMT2ACYP3A4
Bromoxynil SCHEMBL466353 0.97 TTR (0.95) TTRALBMEN1KMT2ACYP3A4
Bromoxynil SCHEMBL7061086 0.91 TTR (0.83) TTRALBMEN1KMT2ACYP3A4
SCHEMBL30689086 0.88 TTR (0.78) TTRALBMEN1KMT2ACYP3A4
SCHEMBL20906090 0.88 TTR (0.78) TTRALBMEN1KMT2ACYP3A4
Bromoxynil SCHEMBL8466645 0.87 TTR (0.76) TTRALBMEN1KMT2ACYP3A4
Bromoxynil SCHEMBL9863697 0.87 TTR (0.76) TTRALBMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115707690-A 3-isoxazolidinone compound, preparation method thereof, weeding composition and application 青岛清原化合物有限公司 2023-02-21 CN disclosed
EP-3092310-A1 RNA-GUIDED GENE DRIVES President and Fellows of Harvard College (US) 2016-11-16 EP disclosed
WO-2015105928-A9 RNA-GUIDED GENE DRIVES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-09-24 WO disclosed
WO-2015105928-A1 RNA-GUIDED GENE DRIVES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-07-16 WO disclosed
US-5977026-A SYNERGISTIC AMERICAN CYANAMID (US) 1999-11-02 US disclosed
US-5925594-A APPLYING TO PLANTS ACETOHYDROXY ACID SYNTHASE-INHIBITING HERBICIDE, NON-ACETOHYDROXY ACID SYNTHASE-INHIBITING HERBICIDE, IMAZAPYR AMERICAN CYANAMID COMPANY (US) 1999-07-20 US disclosed
US-5859283-A TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE RHONE-POULENC AGRICULTURE LIMITED (GB) 1999-01-12 US disclosed
US-5856274-A 4-benzoyl isoxazoles and their use as herbicides RHONE-POULENC AGRICULTURE LIMITED (GB) 1999-01-05 US disclosed
US-5849928-A Herbicidal isoxazole and 2-cyano-1,3-dione compounds RHONE-POULENC AGRICULTURE LIMITED (GB) 1998-12-15 US disclosed
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 EP disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 WO disclosed
WO-1992004827-A1 HERBICIDAL SUBSTITUTED BICYCLIC TRIAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-02 WO disclosed
EP-0463054-A1 SELECTIVE OXABICYCLOALKANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-02 EP disclosed
EP-0413730-A1 HERBICIDAL PYRIDINESULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-02-27 EP disclosed
WO-1990010634-A1 SELECTIVE OXABICYCLOALKANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-20 WO disclosed
WO-1990002130-A2 HERBICIDES FOR WEED CONTROL IN SUGAR BEETS, OILSEED RAPE AND COLE CROPS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-08 WO disclosed
WO-1989010694-A1 HERBICIDAL PYRIDINESULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-16 WO disclosed
US-4813999-A Herbicidal products based on bromoxynil and/or ioxynil esters COMPAGNIE FRANCAISE DE PRODUITS INDUSTRIELS (FR) 1989-03-21 US disclosed
EP-0019796-A1 Propionic acid esters, preparation of these compounds, herbicides containing these compounds as active substances, and the use of such compounds and agents for combating weeds F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-12-10 EP disclosed
US-4185992-A Imidazole derivatives MAY & BAKER LIMITED (GB) 1980-01-29 US disclosed