Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061692 | 0.93 | RARB (0.46) | RARBPTPN11MEN1USP2ALDH1A1 | |
| SCHEMBL7056375 | 0.91 | RARB (0.50) | RARBPTPN11MEN1USP2ALDH1A1 | |
| SCHEMBL7059029 | 0.83 | RARB (0.48) | RARBMEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL17445757 | 0.83 | RARB (0.63) | RARBPTPN11MEN1USP2ALDH1A1 | |
| SCHEMBL7735955 | 0.83 | RARB (0.53) | RARBPTPN11MEN1USP2ALDH1A1 | |
| SCHEMBL9497150 | 0.82 | NR5A1 (0.49) | RARBPTPN11CYP3A4PLA2G4BTSHR | |
| SCHEMBL9494859 | 0.82 | NR5A1 (0.49) | RARBPTPN11CYP3A4PLA2G4BTSHR | |
| SCHEMBL6656815 | 0.82 | NR5A1 (0.49) | RARBPTPN11CYP3A4PLA2G4BTSHR | |
| SCHEMBL10536207 | 0.82 | NR5A1 (0.49) | RARBPTPN11CYP3A4PLA2G4BTSHR | |
| SCHEMBL9493967 | 0.82 | NR5A1 (0.49) | RARBPTPN11CYP3A4PLA2G4BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086194-B1 | MONOSTABLE FERROELECTRIC ACTIVE MATRIX DISPLAY | AVENTIS RES & TECH GMBH & CO (DE) | 2003-05-21 | — | — | EP | disclosed |
| US-6551668-B1 | Monodomain liquid crystal layer with an unambiguously defined direction of the layer normal z of the smectite phase wherein the layer normal z and the preferential direction n of the nematic or cholesteric phase (N* phase) form an angle of >/= 5 | AVENTIS RESEARCH & TECHNOLOGIES (DE) | 2003-04-22 | — | — | US | disclosed |