SCHEMBL7735955

SCHEMBL7735955

CCCCCCOc1ccc(F)c(-c2ccc(CCCCCC)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.53
MCL1 Q07820 1/20 0.53
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPK1 P28482 1/20 0.52
CASP1 P29466 1/20 0.52
KMT2A Q03164 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
SLCO1B3 Q9NPD5 1/20 0.52
SLCO1B1 Q9Y6L6 1/20 0.52
FFAR1 O14842 4/20 0.52
FFAR4 Q5NUL3 3/20 0.52
PTPN11 Q06124 2/20 0.49
RARA P10276 1/20 0.47
RARG P13631 1/20 0.47
CNR2 P34972 2/20 0.45
S1PR1 P21453 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9496973 0.90 RARB (0.57) RARBMEN1USP2ALDH1A1LMNA
SCHEMBL17445757 0.89 RARB (0.63) RARBMEN1USP2ALDH1A1LMNA
SCHEMBL7056375 0.88 RARB (0.50) RARBMCL1MEN1USP2ALDH1A1
SCHEMBL9493683 0.85 RARB (0.58) RARBMCL1MEN1USP2ALDH1A1
SCHEMBL9494727 0.85 RARB (0.58) RARBMCL1MEN1USP2ALDH1A1
SCHEMBL9513744 0.84 RARB (0.60) RARBMEN1USP2ALDH1A1LMNA
SCHEMBL9497822 0.83 MEN1 (0.58) RARBMEN1USP2ALDH1A1LMNA
SCHEMBL10533751 0.83 MEN1 (0.58) RARBMEN1USP2ALDH1A1LMNA
SCHEMBL9494070 0.83 MEN1 (0.58) RARBMEN1USP2ALDH1A1LMNA
SCHEMBL9493809 0.83 MEN1 (0.58) RARBMEN1USP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6403172-B1 6-HEXYLOXY-3-FLUORO-2-(4-HEXYLPHENYL) BENZO(B)THIOPHENE AS FERROELECTRIC SWITCHES OR DISPLAYING DEVICES; DIELECTRIC ANISOTROPY CLARIANT INTERNATIONAL LTD. (CH) 2002-06-11 US disclosed