Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064930 | 0.88 | S1PR1 (0.39) | HPGDTHRATHRBPTPN11 | |
| SCHEMBL7792455 | 0.78 | HTR1D (0.37) | RARBRARANR5A1CYP3A4CYP2D6 | |
| SCHEMBL5722671 | 0.78 | HTR1D (0.37) | RARBRARANR5A1CYP3A4CYP2D6 | |
| SCHEMBL11140514 | 0.77 | CYP3A4 (0.49) | RARBNR5A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11139616 | 0.77 | CYP3A4 (0.49) | RARBNR5A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11145188 | 0.77 | CYP3A4 (0.49) | RARBNR5A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11144888 | 0.77 | CYP3A4 (0.49) | RARBNR5A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11141466 | 0.77 | CYP3A4 (0.49) | RARBNR5A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11136139 | 0.77 | CYP3A4 (0.49) | RARBNR5A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11142485 | 0.77 | CYP3A4 (0.49) | RARBNR5A1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027403-B1 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | AVENTIS RES & TECH GMBH & CO (DE) | 2003-05-28 | — | — | EP | disclosed |
| US-6485797-B1 | 5-Arylindane derivatives and ferroelectric liquid crystal mixture containing same | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2002-11-26 | — | — | US | disclosed |
| EP-1027403-A2 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | Aventis Research & Technologies GmbH & Co. KG (DE) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999019420-A2 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-22 | — | — | WO | disclosed |