Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061245 | 0.88 | RARB (0.41) | THRATHRBPTPN11HPGD | |
| SCHEMBL9483389 | 0.79 | THRA (0.53) | S1PR1S1PR3S1PR4S1PR5THRA | |
| SCHEMBL9477667 | 0.79 | THRA (0.53) | S1PR1S1PR3S1PR4S1PR5THRA | |
| SCHEMBL9484995 | 0.79 | THRA (0.53) | S1PR1S1PR3S1PR4S1PR5THRA | |
| SCHEMBL9484258 | 0.79 | THRA (0.53) | S1PR1S1PR3S1PR4S1PR5THRA | |
| SCHEMBL9484989 | 0.79 | THRA (0.53) | S1PR1S1PR3S1PR4S1PR5THRA | |
| SCHEMBL9399556 | 0.78 | THRA (0.52) | S1PR1S1PR3S1PR4S1PR5THRA | |
| SCHEMBL9484097 | 0.78 | THRA (0.52) | S1PR1S1PR3S1PR4S1PR5THRA | |
| SCHEMBL9484969 | 0.78 | THRA (0.51) | S1PR1S1PR3S1PR4S1PR5THRA | |
| SCHEMBL9486073 | 0.76 | THRA (0.51) | S1PR1S1PR3S1PR4S1PR5THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027403-B1 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | AVENTIS RES & TECH GMBH & CO (DE) | 2003-05-28 | — | — | EP | disclosed |
| US-6485797-B1 | 5-Arylindane derivatives and ferroelectric liquid crystal mixture containing same | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2002-11-26 | — | — | US | disclosed |
| EP-1027403-A2 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | Aventis Research & Technologies GmbH & Co. KG (DE) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999019420-A2 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-22 | — | — | WO | disclosed |