Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226638 | 0.92 | HMGCR (0.48) | HMGCRNR1I2GABBR2GABBR1GPR55 | |
| SCHEMBL6917885 | 0.86 | HMGCR (0.53) | HMGCRNR1I2GABBR2GABBR1GPR55 | |
| SCHEMBL5669988 | 0.86 | HMGCR (0.49) | HMGCRNR1I2NPSR1LMNACYP1A2 | |
| SCHEMBL5671320 | 0.84 | HMGCR (0.40) | HMGCRNR1I2GABBR2GABBR1GPR55 | |
| SCHEMBL9227380 | 0.81 | HMGCR (0.48) | HMGCRNR1I2GABBR2GABBR1GPR55 | |
| SCHEMBL9276664 | 0.81 | HMGCR (0.55) | HMGCRNR1I2GABBR2GABBR1GPR55 | |
| SCHEMBL9276670 | 0.81 | HMGCR (0.55) | HMGCRNR1I2GABBR2GABBR1GPR55 | |
| SCHEMBL9222763 | 0.80 | HMGCR (0.49) | HMGCRNR1I2GABBR2GABBR1GPR55 | |
| SCHEMBL7061566 | 0.80 | HMGCR (0.55) | HMGCRNR1I2GABBR2GABBR1GPR55 | |
| SCHEMBL6910765 | 0.79 | GABBR2 (0.52) | HMGCRNR1I2GABBR2GABBR1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | claimed |