⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566580 | 0.69 | — | — | |
| SCHEMBL990358 | 0.69 | — | — | |
| SCHEMBL608065 | 0.69 | — | — | |
| SCHEMBL19381564 | 0.67 | KDM1A (0.31) | — | |
| SCHEMBL1561090 | 0.67 | — | — | |
| SCHEMBL24426096 | 0.66 | — | — | |
| SCHEMBL25076066 | 0.65 | — | — | |
| SCHEMBL866571 | 0.65 | — | — | |
| SCHEMBL10593788 | 0.64 | — | — | |
| SCHEMBL16911474 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285324-B1 | PREPARATION OF SUBSTITUTED FLUOROBENZENES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-11-27 | — | — | EP | claimed |
| EP-0285324-A1 | Preparation of substituted fluorobenzenes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-05 | — | — | EP | claimed |
| US-4754084-A | PYROLYSIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-28 | — | — | US | claimed |
| EP-1094053-B1 | Method of preparing fluoroaromatic compounds | ZELINSKY INST OF ORGANIC CHEMI (RU) | 2003-05-21 | — | — | EP | disclosed |
| EP-1094053-A1 | Method of preparing fluoroaromatic compounds | Zelinsky Institute of Organic Chemistry (RU) | 2001-04-25 | — | — | EP | disclosed |
| US-6008407-A | REACTING CHLOROTRIFLUOROETHYLENE AND 1,3-BUTADIENE TO PRODUCE CHLOROTRIFLUOROCYCLOHEXENES, DEHYDROHALOGENATING THE MIXTURE OF CYCLOHEXENES WITH PHASE TRANSFER CATALYST IN PRESENCE OF ALKALI METAL HYDROXIDE WITHOUT SOLVENT | ZELINSKY INSTITUTE OF ORGANIC CHEMISTRY (RU) | 1999-12-28 | — | — | US | disclosed |
| EP-0493030-A1 | Preparation of difluorobenzenes | RHONE-POULENC CHEMICALS LIMITED (GB) | 1992-07-01 | — | — | EP | disclosed |
| EP-0285324-B1 | PREPARATION OF SUBSTITUTED FLUOROBENZENES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| WO-1991013847-A1 | PROCESS FOR PREPARING CHLORO-DIFLUOROBENZENE | ISC CHEMICALS LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447259-A1 | Process for preparing chloro-difluorobenzene | ISC CHEMICALS LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |
| EP-0285324-A1 | Preparation of substituted fluorobenzenes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |
| EP-0285324-A1 | Preparation of substituted fluorobenzenes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4754084-A | PYROLYSIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| US-4754084-A | PYROLYSIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-28 | — | — | US | disclosed |