⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979571 | 0.93 | — | — | |
| SCHEMBL9191038 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL29213148 | 0.83 | — | — | |
| SCHEMBL20054185 | 0.78 | — | — | |
| SCHEMBL29578630 | 0.73 | — | — | |
| SCHEMBL24694607 | 0.69 | KDM1A (0.30) | — | |
| SCHEMBL16486342 | 0.69 | NEK2 (0.32) | — | |
| SCHEMBL7061491 | 0.69 | — | — | |
| SCHEMBL608065 | 0.67 | — | — | |
| SCHEMBL23547282 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969716-B2 | Indole derivatives as modulators of methyl modifying enzymes, compositions and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2018-05-15 | — | — | US | claimed |
| US-20160185757-A1 | INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2016-06-30 | — | — | US | claimed |
| EP-3033334-A1 | INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2016-06-22 | — | — | EP | claimed |
| WO-2015023915-A1 | INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2015-02-19 | — | — | WO | claimed |
| US-4001205-A | WATER-SOLUBLE, FIBER-REACTIVE PHENYLAZODIHYDROXY, METHYL, CYANOPYRIDINE DYESTUFFS | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | claimed |
| CN-119730843-A | Substituted pyrrolidinyl and piperidinyl compounds and related methods of treatment | 阿尔克姆斯有限公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20240294500-A1 | ISOINDOLINONE COMPOUNDS, AND USES THEREOF | HANGZHOU GLUBIO PHARMACEUTICAL CO., LTD. (CN) | 2024-09-05 | — | — | US | disclosed |
| EP-4352046-A1 | ISOINDOLINONE COMPOUNDS, AND USES THEREOF | Hangzhou Glubio Pharmaceutical Co., Ltd. (CN) | 2024-04-17 | — | — | EP | disclosed |
| US-20240101528-A1 | SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-03-28 | — | — | US | disclosed |
| CN-117561244-A | Isoindolinone compounds and uses thereof | 杭州格博生物医药有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-116897152-A | Substituted pyrazolylpiperidine carboxylic acids | 拜耳公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-116829545-A | Substituted pyrazolylpiperidine carboxylic acids | 拜耳公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2022257897-A1 | ISOINDOLINONE COMPOUNDS, AND USES THEREOF | HANGZHOU GLUBIO PHARMACEUTICAL CO., LTD. (CN) | 2022-12-15 | — | — | WO | disclosed |
| US-9969716-B2 | Indole derivatives as modulators of methyl modifying enzymes, compositions and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20160185757-A1 | INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2016-06-30 | — | — | US | disclosed |
| EP-3033334-A1 | INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2016-06-22 | — | — | EP | disclosed |
| WO-2015023915-A1 | INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2015-02-19 | — | — | WO | disclosed |
| US-20120189546-A1 | Radiolabelling Method Using Cycloalkyl Groups | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-07-26 | — | — | US | disclosed |
| EP-2454230-A1 | RADIOLABELLING METHOD USING CYCLOALKYL GROUPS | Bayer Pharma Aktiengesellschaft (DE) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006621-A1 | RADIOLABELLING METHOD USING CYCLOALKYL GROUPS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-01-20 | — | — | WO | disclosed |