Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610739 | 0.94 | TSHR (0.60) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL21292110 | 0.90 | THRB (0.61) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL245045 | 0.90 | THRB (0.61) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL22554429 | 0.89 | TSHR (0.83) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL22554413 | 0.89 | TSHR (0.83) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL22554406 | 0.89 | TSHR (0.83) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL22023212 | 0.89 | TSHR (0.83) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL22554400 | 0.89 | TSHR (0.83) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL22554427 | 0.89 | TSHR (0.83) | TSHRTDP1POLBAPEX1HTT | |
| SCHEMBL5607699 | 0.89 | TSHR (0.83) | TSHRTDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823458-B1 | POLYMERIC MATERIAL, MEDICAL MATERIAL AND LIQUID POLYMER COMPOSITION | NOF CORP (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-5977257-A | Polymer material, medical material and liquid high molecular composition | NOF CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0823458-A1 | POLYMERIC MATERIAL, MEDICAL MATERIAL AND LIQUID POLYMER COMPOSITION | NOF CORPORATION (JP) | 1998-02-11 | — | — | EP | disclosed |