SCHEMBL7061632

SCHEMBL7061632

C=CCOOOC(=O)CC

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PKM P14618 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30083352 0.87
SCHEMBL1920831 0.78 CYP3A4 (0.33) TSHRCYP3A4MAPT
SCHEMBL28109341 0.77 TSHR (0.46) TSHRALDH1A1SMN1; SMN2PKMTDP1
SCHEMBL905558 0.76
SCHEMBL28592920 0.75 TSHR (0.43) TSHRALDH1A1KDM4ECYP3A4SMN1; SMN2
SCHEMBL6535087 0.74 ALDH1A1 (0.43) TSHRALDH1A1SMN1; SMN2TDP1
SCHEMBL28619491 0.73 MEN1 (0.39) TSHRALDH1A1TDP1POLB
SCHEMBL194711 0.73
SCHEMBL7781355 0.72 CYP3A4 (0.31) CYP3A4
SCHEMBL31443217 0.72 TSHR (0.49) TSHRALDH1A1KDM4ECYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787750-B1 Poly(alkylethylene) structural isomers BOREALIS GMBH (AT) 2003-05-14 EP disclosed
EP-0787750-A2 Poly(alkylethylene) structural isomers PCD-Polymere Gesellschaft m.b.H. (AT) 1997-08-06 EP disclosed