Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29385052 | 1.00 | CCR2 (0.45) | CCR2KCNH2SCN9ADGAT2GRIN1 | |
| SCHEMBL70204 | 0.92 | CCR2 (0.47) | CCR2KCNH2 | |
| SCHEMBL29381956 | 0.92 | CCR2 (0.47) | CCR2KCNH2 | |
| SCHEMBL69059 | 0.91 | EPHX2 (0.41) | CCR2SCN9AGRIN1GRIN2B | |
| SCHEMBL29381918 | 0.91 | EPHX2 (0.41) | CCR2SCN9AGRIN1GRIN2B | |
| SCHEMBL70427 | 0.85 | EPHX2 (0.46) | CCR2KCNH2SCN9A | |
| SCHEMBL29384502 | 0.85 | EPHX2 (0.46) | CCR2KCNH2SCN9A | |
| SCHEMBL29382083 | 0.83 | EPHX2 (0.49) | CCR2 | |
| SCHEMBL68443 | 0.83 | EPHX2 (0.49) | CCR2 | |
| SCHEMBL70272 | 0.82 | SCN9A (0.39) | CCR2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268143-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | Forest Laboratories Holdings Limited (BM) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009117676-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | WO | disclosed |