Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 14/20 | 0.58 |
| ▸ | PLG | P00747 | 1/20 | 0.58 |
| ▸ | PROC | P04070 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 12/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.56 |
| ▸ | F9 | P00740 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065469 | 0.94 | PRSS1 (0.56) | F10PRSS1PLGPROCF2 | |
| SCHEMBL6987087 | 0.87 | F10 (0.55) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7065403 | 0.85 | F10 (0.58) | F10PRSS1PLGPROCF2 | |
| SCHEMBL7065720 | 0.83 | F10 (0.61) | F10PRSS1PLGPROCF2 | |
| SCHEMBL7065854 | 0.82 | F10 (0.60) | F10PRSS1PLGPROCF2 | |
| SCHEMBL7062348 | 0.81 | F10 (0.63) | F10PRSS1PLGPROCF2 | |
| SCHEMBL6986465 | 0.81 | F2 (0.54) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7059855 | 0.80 | F10 (0.62) | F10PRSS1PLGPROCF2 | |
| SCHEMBL7062357 | 0.79 | F10 (0.61) | F10PRSS1PLGPROCF2 | |
| SCHEMBL7062113 | 0.79 | F10 (0.63) | F10PRSS1PLGPROCF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176465-A1 | Cyclic amino acid derivatives | MERCK PATENT GMBH (DE) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176465-A1 | Cyclic amino acid derivatives | F5, F11, F2 | F10 5/4885PRSS1 298/4885PLG 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.