SCHEMBL7062263

SCHEMBL7062263

C=CCC(C)c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.44
ACHE P22303 2/20 0.44
GRIA4 P48058 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CHRNA7 P36544 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 2/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
ALOX5 P09917 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
ANXA2 P07355 1/20 0.32
S100A10 P60903 1/20 0.32
MAOA P21397 2/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3671591 0.81 ALDH1A1 (0.46) GRIA4CHRNA7TDP1ALDH1A1CYP2C19
SCHEMBL19416602 0.81 SLC6A2 (0.36) SLC6A2ALDH1A1
SCHEMBL11463951 0.81 ESR1 (0.53) SLC6A2SLC6A3TDP1ALDH1A1CYP2C19
SCHEMBL3022203 0.80 TAAR1 (0.52) ALDH1A1CYP2C19TAAR1
SCHEMBL19285046 0.80 TAAR1 (0.52) ALDH1A1CYP2C19TAAR1
SCHEMBL5146817 0.79 SLC6A2 (0.36) STAT3ACHEGRIA4SLC6A2SLC6A3
SCHEMBL11295091 0.78 STAT3 (0.49) STAT3ACHEGRIA4SLC6A3CHRNA7
SCHEMBL7435987 0.77 CHRNA7 (0.40) STAT3ACHESLC6A2SLC6A3CHRNA7
SCHEMBL3245046 0.77 HRH3 (0.43) STAT3ACHESLC6A2SLC6A3CHRNA7
SCHEMBL10640597 0.77 STAT3 (0.43) STAT3ACHEGRIA4CHRNA7TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030153704-A1 Polymer-coated metal composites by dip autopolymerization BELL JAMES P (US) 2003-08-14 US disclosed
US-6555239-B1 Dipping the metal substrate in an acidic solution of 4-carboxyphenyl maleimide, and n-phenyl maleimide, 2-(methacryloyloxy)ethyl acetoacetate, methyl methacrylate or acrylonitrile for a time in the absence of other catalysts THE UNIVERSITY OF CONNECTICUT 2003-04-29 US disclosed
US-6451383-B2 APPLYING AN ACIDIC STARTING SOLUTION OF AN EMULSION OF CHEMICALLY DISTINCT MONOMERS TO A METAL SUBSTRATE WHICH CAN INITIATE POLYMERIZATION THE UNIVERSITY OF CONNECTICUT 2002-09-17 US disclosed
CN-1082400-C Method for forming polymer coating on metal substrate UNIV CONNECTICUT (US) 2002-04-10 CN disclosed
US-6355354-B1 FOR CORROSION AND EROSION RESISTANCE, ABRASION RESISTANCE, AND ELECTRICAL AND THERMAL INSULATION THE UNIVERSITY OF CONNECTICUT 2002-03-12 US disclosed
US-20010051223-A1 Polymer-coated metal composites by dip autopolymerization BELL JAMES P (US) 2001-12-13 US disclosed
EP-0917495-A4 COMPOSITION AND METHOD FOR COATING METALS BY DIP AUTOPOLYMERIZATION UNIV CONNECTICUT (US) 2001-04-25 EP disclosed
CN-1226848-A Composition and method for coating metals by dip autopolymerization UNIV CONNECTICUT (US) 1999-08-25 CN disclosed
EP-0917495-A1 COMPOSITION AND METHOD FOR COATING METALS BY DIP AUTOPOLYMERIZATION THE UNIVERSITY OF CONNECTICUT (US) 1999-05-26 EP disclosed
US-5807612-A FORMING DECORATIVE OR PROTECTIVE OVERCOATING THE UNIVERSITY OF CONNECTICUT (US) 1998-09-15 US disclosed
WO-1998005436-A1 COMPOSITION AND METHOD FOR COATING METALS BY DIP AUTOPOLYMERIZATION THE UNIVERSITY OF CONNECTICUT (US) 1998-02-12 WO disclosed