Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 10/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6097023 | 0.79 | LRRK2 (0.54) | AKR1C3MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6093674 | 0.78 | LRRK2 (0.58) | SGMS2LRRK2 | |
| SCHEMBL6094843 | 0.77 | NPC1 (0.51) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6097040 | 0.76 | GAA (0.48) | SGMS2AKR1C3MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6096161 | 0.76 | MAOB (0.54) | SGMS2AKR1C3MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6096041 | 0.76 | MEN1 (0.48) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6096243 | 0.76 | LRRK2 (0.54) | SGMS2AKR1C3MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6095316 | 0.73 | NPC1 (0.46) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6094102 | 0.73 | LRRK2 (0.53) | SGMS2LRRK2 | |
| SCHEMBL5860138 | 0.72 | PSMD14 (0.49) | MAPTSMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314712-A1 | NF-KAPPA-B INHIBITOR CONTAINING SUBSTITUTED BENZOIC ACID DERIVATIVE AS ACTIVE INGREDIENT | Daiichi Suntory Pharma Co., Ltd. (JP) | 2003-05-28 | — | — | EP | disclosed |