Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | AR | P10275 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16553424 | 0.93 | HIF1A (0.56) | HIF1AHTTARKMT2AMEN1 | |
| SCHEMBL376300 | 0.86 | HIF1A (0.61) | HIF1AHTTARKMT2AMEN1 | |
| SCHEMBL2768639 | 0.85 | HIF1A (0.59) | HIF1AHTTARKMT2AMEN1 | |
| SCHEMBL11964790 | 0.83 | HTT (0.67) | HIF1AHTTARKMT2AMEN1 | |
| SCHEMBL868711 | 0.83 | AR (0.85) | HIF1AHTTARKMT2AMEN1 | |
| SCHEMBL12363856 | 0.83 | AR (0.85) | HIF1AHTTARKMT2AMEN1 | |
| SCHEMBL18653613 | 0.83 | HIF1A (0.58) | HIF1AHTTARKMT2AMEN1 | |
| SCHEMBL28556067 | 0.82 | LMNA (0.50) | HTTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL484242 | 0.82 | LMNA (0.50) | HTTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6939521 | 0.82 | HTT (0.65) | HIF1AHTTARKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825240-B2 | A BINDER OF A BLEND OF AN AMORPHOUS AND A CRYSTALLINE URETHANE ACRYLATE AN ADDITIVE EXCLUDING AN ULTRAVIOLET INITIATOR; STORAGE STABLE AT 35 DEGREES C.; WEATHERPROOFING; HARDNESS; GRINDING WITHOUT REFRIGERANT; FLEXIBILITY | DEGUSSA AG (DE) | 2004-11-30 | — | — | US | disclosed |
| US-20030130372-A1 | A binder of a blend of an amorphous and a crystalline urethane acrylate an additive excluding an ultraviolet initiator; storage stable at 35 degrees C.; weatherproofing; hardness; grinding without refrigerant; flexibility | DEGUSSA AG (DE) | 2003-07-10 | — | — | US | disclosed |