SCHEMBL70626

SCHEMBL70626

COC(=O)Cc1ccc(CC(=O)OC)n1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
MAPT P10636 3/20 0.45
TSHR P16473 3/20 0.45
EGFR P00533 1/20 0.45
HPGD P15428 1/20 0.45
HSP90AB1 P08238 1/20 0.44
ALDH1A1 P00352 6/20 0.41
HSD17B10 Q99714 3/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
GAA P10253 4/20 0.41
GFER P55789 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.40
KDM4E B2RXH2 4/20 0.39
CXCL8 P10145 1/20 0.38
AKR1B1 P15121 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1125985 0.92 CYP4F2 (0.44) CYP4F2CYP4A11MAPTTSHREGFR
SCHEMBL10174695 0.92 TSHR (0.41) CYP4F2CYP4A11MAPTTSHREGFR
SCHEMBL11881716 0.84 CXCL8 (0.41) CYP4F2CYP4A11MAPTTSHREGFR
SCHEMBL11454589 0.82 AR (0.43) CYP4F2CYP4A11MAPTTSHREGFR
SCHEMBL12255397 0.81 KDM4E (0.43) MAPTHPGDALDH1A1HSD17B10KMT2A
SCHEMBL12255157 0.81 NPSR1 (0.37) MAPTTSHREGFRHPGDHSP90AB1
SCHEMBL12255221 0.80 MAPK1 (0.40) CYP4F2CYP4A11MAPTTSHREGFR
SCHEMBL11371392 0.79 CXCL8 (0.57) MAPTTSHREGFRHPGDALDH1A1
SCHEMBL3999226 0.78 CXCL8 (0.72) MAPTHPGDALDH1A1KMT2ALMNA
SCHEMBL12255340 0.78 MAPT (0.35) CYP4F2CYP4A11MAPTTSHREGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CYP4F2 2876/4885CYP4A11 1392/4885MAPT 1923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.