Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229831 | 1.00 | TSHR (0.45) | TSHRALDH1A1KMT2ASLC6A3SLC6A4 | |
| SCHEMBL6232109 | 1.00 | TSHR (0.45) | TSHRALDH1A1KMT2ASLC6A3SLC6A4 | |
| SCHEMBL6233893 | 0.89 | TSHR (0.45) | TSHRSLC6A3 | |
| SCHEMBL6231643 | 0.89 | TSHR (0.45) | TSHRSLC6A3 | |
| SCHEMBL7067185 | 0.87 | TSHR (0.58) | TSHRSLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6231716 | 0.87 | PKM (0.44) | TSHRALDH1A1KMT2ASLC6A3SLC6A4 | |
| SCHEMBL6233365 | 0.87 | PKM (0.44) | TSHRALDH1A1KMT2ASLC6A3SLC6A4 | |
| SCHEMBL7062139 | 0.87 | CHRNA1 (0.43) | TSHRALDH1A1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7068098 | 0.87 | PKM (0.44) | TSHRALDH1A1KMT2ASLC6A3SLC6A4 | |
| SCHEMBL6231109 | 0.87 | TSHR (0.58) | TSHRSLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |