Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067745 | 0.84 | DPP7 (0.66) | DPP7SMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL6824217 | 0.84 | DPP7 (0.65) | DPP7MEN1KMT2AHPGDGAA | |
| SCHEMBL6824539 | 0.83 | DPP7 (0.61) | DPP7MEN1KMT2AHPGDTSHR | |
| SCHEMBL2580284 | 0.78 | DPP7 (0.55) | DPP7MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2580281 | 0.78 | DPP7 (0.54) | DPP7MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7366398 | 0.77 | DPP7 (0.71) | DPP7SMN1; SMN2DPP4DPP8NPC1 | |
| SCHEMBL1039399 | 0.75 | HDAC8 (0.68) | DPP7HPGDDPP4TSHRGAA | |
| SCHEMBL8077871 | 0.75 | HDAC8 (0.68) | DPP7HPGDDPP4TSHRGAA | |
| SCHEMBL1040335 | 0.73 | HDAC8 (0.69) | DPP7HPGDDPP4TSHRGAA | |
| SCHEMBL368452 | 0.73 | HDAC8 (0.69) | DPP7HPGDDPP4TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |