Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | LAP3 | P28838 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366398 | 0.91 | DPP7 (0.71) | DPP7NPC1RAB9ACASP3SENP8 | |
| SCHEMBL6824539 | 0.88 | DPP7 (0.61) | DPP7 | |
| SCHEMBL7062901 | 0.84 | DPP7 (0.68) | DPP7NPC1RAB9ACASP3SENP8 | |
| SCHEMBL8190798 | 0.81 | DPP7 (0.59) | DPP7HRH3SMN1; SMN2TP53CACNA1B | |
| SCHEMBL7372150 | 0.80 | DPP7 (0.57) | DPP7NPC1RAB9ALTA4HTP53 | |
| SCHEMBL7371854 | 0.80 | DPP7 (0.57) | DPP7NPC1RAB9ALTA4HTP53 | |
| SCHEMBL7403643 | 0.80 | DPP4 (0.61) | DPP7LTA4HLAP3 | |
| SCHEMBL7340762 | 0.79 | CACNA1B (0.59) | DPP7CACNA1B | |
| SCHEMBL7371920 | 0.79 | NPC1 (0.58) | DPP7NPC1RAB9ALTA4HLAP3 | |
| SCHEMBL7369861 | 0.79 | FAAH (0.62) | DPP7NPC1RAB9AHRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |