Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.55 |
| ▸ | ESR1 | P03372 | 5/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2112355 | 0.85 | ESR1 (0.59) | PARP1ESR1ESR2ALDH1A1TSHR | |
| SCHEMBL29251036 | 0.83 | PARP10 (0.40) | PARP1ESR1ESR2ALDH1A1TSHR | |
| SCHEMBL2111092 | 0.83 | ESR1 (0.60) | ESR1ESR2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL2113067 | 0.83 | ESR1 (0.51) | PARP1ESR1ESR2ALDH1A1TSHR | |
| SCHEMBL17292700 | 0.81 | PARP1 (0.42) | PARP1ALDH1A1TSHRCYP3A4PARP10 | |
| SCHEMBL5076006 | 0.80 | POLB (0.58) | PARP1ESR1ESR2ALDH1A1TSHR | |
| SCHEMBL7064897 | 0.79 | ESR1 (0.58) | PARP1ESR1ESR2ALDH1A1TSHR | |
| SCHEMBL11804404 | 0.78 | ALDH1A1 (0.52) | PARP1ALDH1A1TSHRCYP3A4HSD17B10 | |
| SCHEMBL18063674 | 0.77 | PARP1 (0.55) | PARP1ESR1ESR2TSHRCYP3A4 | |
| SCHEMBL28629411 | 0.76 | PARP1 (0.42) | PARP1ESR1ESR2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608163-B2 | From bisphenol A and a hydroxyphenyl-substituted terephthalimide; improved resistance to dilute caustic solution; use in automatic dishwater parts | GENERAL ELECTRIC COMPANY | 2003-08-19 | — | — | US | claimed |
| US-6608163-B2 | From bisphenol A and a hydroxyphenyl-substituted terephthalimide; improved resistance to dilute caustic solution; use in automatic dishwater parts | GENERAL ELECTRIC COMPANY | 2003-08-19 | — | — | US | disclosed |