SCHEMBL7063227

SCHEMBL7063227

CCC(C)(C)c1ccc(OCC(=O)Nc2cccc(C(N)=O)c2)c(C(C)(C)CC)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 7/20 0.54
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
ALDH1A1 P00352 4/20 0.54
MAPK1 P28482 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
HIF1A Q16665 3/20 0.50
EPAS1 Q99814 3/20 0.50
MDH1 P40925 1/20 0.48
MDH2 P40926 1/20 0.48
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
MITF O75030 2/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
PAX8 Q06710 1/20 0.47
KLF5 Q13887 1/20 0.47
MAPT P10636 4/20 0.45
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11703999 0.92 ALDH1A1 (0.56) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1
SCHEMBL7063221 0.91 SMN1; SMN2 (0.55) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1
SCHEMBL10525796 0.90 SMN1; SMN2 (0.56) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1
SCHEMBL8621071 0.89 MEN1 (0.55) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1
SCHEMBL11793477 0.88 SMN1; SMN2 (0.52) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1
SCHEMBL9340133 0.86 SMN1; SMN2 (0.61) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1
SCHEMBL9289464 0.86 SMN1; SMN2 (0.48) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1
SCHEMBL10525777 0.85 SMN1; SMN2 (0.51) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1
SCHEMBL6536704 0.84 SMN1; SMN2 (0.54) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1
SCHEMBL7747075 0.84 MEN1 (0.54) SMN1; SMN2MEN1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310619-A LIGHT SENSITIVE ELEMENT COMPRISING A 5-PYRAZOLONE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US claimed
US-4308343-A MAGENTA 2-EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US claimed
US-4301235-A A PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-11-17 US claimed
US-6620580-B2 Photographic element comprising a support bearing a blue light sensitive record containing at least three layers having different levels of light sensitivity arranged in the order slowest to fastest with the slowest layer closest to the EASTMAN KODAK COMPANY 2003-09-16 US disclosed
US-20030143498-A1 Color negative element containing triple-coated blue record and method of imaging using same EASTMAN KODAK COMPANY 2003-07-31 US disclosed
EP-1004932-B1 Photographic and imaging elements including biaxially oriented polyolefin sheets EASTMAN KODAK CO (US) 2003-06-04 EP disclosed
EP-1312978-A1 Color negative element containing triple-coated blue record and method of imaging using same EASTMAN KODAK COMPANY (US) 2003-05-21 EP disclosed
EP-1004932-A1 Photographic and imaging elements including biaxially oriented polyolefin sheets EASTMAN KODAK COMPANY (US) 2000-05-31 EP disclosed
US-6030742-A CURL RESISTANCE; A PHOTOSENSITIVE SILVER HALIDE LAYER COMPRISING AT LEAST ONE DYE FORMING COUPLER, A SUPPORT COMPRISING PAPER HAVING LAMINATED A TOP AND BOTTOM SHEET OF BIAXIALLY ORIENTED POLYETHYLENE EASTMAN KODAK COMPANY (US) 2000-02-29 US disclosed
EP-0671661-B1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1999-08-25 EP disclosed
EP-0596575-B1 Photographic material and process comprising a pyrazolotriazole moiety EASTMAN KODAK CO (US) 1999-01-27 EP disclosed
US-4086094-A HYDROPHILIC COLLOID LAYER FUJI PHOTO FILM CO., LTD. (JA) 1978-04-25 US disclosed
US-4083721-A AROMATIC PRIMARY AMINE DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1978-04-11 US disclosed
US-4076533-A MAGENTA DYE FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed
US-4072525-A COLOR PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1978-02-07 US disclosed
US-4040835-A Two-equivalent magenta couplers with amido coupling-off groups FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4040836-A MAGENTA FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4040829-A SILVER HALIDE EMULSIONS, SEMI-DIFFUSIBLE COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4029508-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1977-06-14 US disclosed
US-4021248-A SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US disclosed