Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.55 |
| ▸ | GCGR | P47871 | 3/20 | 0.47 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.47 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.47 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.47 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.47 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.47 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.47 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.47 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.47 |
| ▸ | GIPR | P48546 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | GLP1R | P43220 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063690 | 0.84 | GCGR (0.64) | TRPV1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL7063692 | 0.84 | GCGR (0.64) | TRPV1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL6918886 | 0.84 | GCGR (0.64) | TRPV1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL6918883 | 0.84 | GCGR (0.64) | TRPV1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL6917348 | 0.81 | TRPV1 (0.47) | TRPV1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL6916113 | 0.75 | GCGR (0.49) | TRPV1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL6918882 | 0.70 | SUCNR1 (0.43) | TRPV1GCGRALDH1A1CYP3A4 | |
| SCHEMBL9072927 | 0.67 | PARP15 (0.44) | NR1H4EPHX2ALDH1A1KDM4EMEN1 | |
| SCHEMBL4097353 | 0.67 | GCGR (0.72) | TRPV1GCGRADCY6ADCY3ADCY9 | |
| SCHEMBL6914028 | 0.67 | NR1H4 (0.47) | TRPV1GCGRADCY6ADCY3ADCY9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762318-B2 | CARBOXYLIC ACID OR TETRAZOLE DERIVATIZED SECONDARY AMIDES; ORAL ADMINISTRATION | NOVO NORDISK A/S (DK) | 2004-07-13 | — | — | US | disclosed |
| US-20030236292-A1 | Stimulant releasing glucose from liver cells; antidiabetic agents | PFIZER INC | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236292-A1 | Stimulant releasing glucose from liver cells; antidiabetic agents | GPR119, GLP1R, GIPR | TRPV1 1946/4885GCGR 4/4885ADCY6 1234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.