SCHEMBL7063731

SCHEMBL7063731

C/C(=C\c1cc(C(=O)O)cs1)c1cc2c(cc1C)SCCC2(C)C

nearest known ligand 0.77

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RARB P10826 17/20 0.77
RARG P13631 16/20 0.77
RXRA P19793 16/20 0.77
RXRB P28702 8/20 0.77
RXRG P48443 8/20 0.77
RARA P10276 11/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7066591 1.00 RARB (0.77) RARBRARGRXRARXRBRXRG
SCHEMBL5894188 0.87 RXRA (1.00) RARBRARGRXRARXRBRXRG
SCHEMBL3685267 0.87 RXRA (1.00) RARBRARGRXRARXRBRXRG
SCHEMBL3685269 0.87 RXRA (1.00) RARBRARGRXRARXRBRXRG
SCHEMBL10936300 0.84 RARB (0.74) RARBRARGRXRARXRBRXRG
SCHEMBL10936302 0.84 RARB (0.74) RARBRARGRXRARXRBRXRG
SCHEMBL10937274 0.81 RXRA (0.77) RARBRARGRXRARXRBRXRG
SCHEMBL10937270 0.81 RXRA (0.77) RARBRARGRXRARXRBRXRG
SCHEMBL10937401 0.80 RARB (0.54) RARBRARGRXRARXRBRXRG
SCHEMBL10937398 0.80 RARB (0.54) RARBRARGRXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0829256-B1 Use of RXR retinoid receptor agonists to stimulate or induce hair growth and/or stop their loss OREAL (FR) 2003-06-04 EP claimed