Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709193 | 0.80 | KCNH2 (0.60) | TMEM97SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL1695397 | 0.78 | TMEM97 (0.51) | TMEM97SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL1695270 | 0.76 | CDK1 (0.47) | TMEM97SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL709359 | 0.75 | CHRM2 (0.80) | TMEM97SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL1549840 | 0.73 | CDK1 (0.45) | TMEM97SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL708741 | 0.73 | CHRM2 (0.56) | TMEM97SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL6433202 | 0.73 | CDK1 (0.50) | TMEM97SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL706212 | 0.72 | CDK1 (0.52) | TMEM97SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL710402 | 0.71 | CDK1 (0.74) | TMEM97SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL1550558 | 0.71 | KDM4E (0.46) | TMEM97SIGMAR1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229908-A1 | Compositions and methods for the treatment of Parkinson's disease and tardive dyskinesias | Greenlee, Winner and Sullivan, P.C. | 2004-11-18 | — | — | US | claimed |