Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067100 | 0.73 | USP2 (0.49) | TSHRHTTSMN1; SMN2USP2POLB | |
| SCHEMBL29087383 | 0.70 | NR3C2 (0.44) | ALDH1A1TSHRHTTHPGDKMT2A | |
| SCHEMBL12000924 | 0.69 | KMT2A (0.56) | ALDH1A1TSHRHTTHPGDKMT2A | |
| SCHEMBL7065804 | 0.69 | SMN1; SMN2 (0.60) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL14676658 | 0.68 | USP2 (0.59) | HTTSMN1; SMN2USP2LMNAGAA | |
| SCHEMBL8354304 | 0.67 | KMT2A (0.57) | ALDH1A1TSHRHTTHPGDKMT2A | |
| SCHEMBL7064210 | 0.67 | USP2 (0.48) | HTTSMN1; SMN2USP2 | |
| SCHEMBL5675304 | 0.66 | USP2 (0.60) | ALDH1A1HTTKMT2ASMN1; SMN2USP2 | |
| Hydrochloric Acid SCHEMBL7522429 | 0.66 | ALDH1A1 (0.50) | ALDH1A1TSHRHTTHPGDKMT2A | |
| SCHEMBL14676247 | 0.66 | USP2 (0.56) | HTTSMN1; SMN2USP2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130251-A1 | Amino lactam sulfonamides as inhibitors of A-beta protein production | THOMPSON LORIN A (US) | 2003-07-10 | — | — | US | disclosed |
| US-6503901-B1 | Alzheimer*s disease and Down*s syndrome treatment | BRISTOL MYERS SQUIBB PHARMA COMPANY | 2003-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130251-A1 | Amino lactam sulfonamides as inhibitors of A-beta protein production | APP, APH1A, BACE1 | ALDH1A1 3364/4885TSHR 4750/4885HTT 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.