Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526950 | 0.89 | ROR1 (0.64) | HSD17B10ABCG2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8069162 | 0.82 | ALDH1A1 (0.65) | HSD17B10ABCG2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8052909 | 0.82 | ABCG2 (0.58) | HSD17B10ABCG2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL24983789 | 0.81 | STING1 (0.41) | ALDH1A1HPGDMAOAMAOB | |
| SCHEMBL24984291 | 0.81 | STING1 (0.41) | ALDH1A1HPGDMAOAMAOB | |
| SCHEMBL24983373 | 0.81 | STING1 (0.41) | ALDH1A1HPGDMAOAMAOB | |
| SCHEMBL13091031 | 0.80 | ABCG2 (0.73) | HSD17B10ABCG2CYP3A4ALDH1A1ACHE | |
| SCHEMBL13091029 | 0.80 | ABCG2 (0.73) | HSD17B10ABCG2CYP3A4ALDH1A1ACHE | |
| SCHEMBL13091033 | 0.80 | ABCG2 (0.73) | HSD17B10ABCG2CYP3A4ALDH1A1ACHE | |
| SCHEMBL28320429 | 0.80 | ROR1 (0.68) | HSD17B10ABCG2CYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638554-B2 | Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL (US) | 2009-12-29 | — | — | US | disclosed |
| US-7329687-B2 | Flavanoid compounds as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL (US) | 2008-02-12 | — | — | US | disclosed |
| US-20030229136-A1 | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229136-A1 | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | FLT1, VEGFA, FLT4 | HSD17B10 414/4885ABCG2 245/4885CYP3A4 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.