Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.41 |
| ▸ | WNT3A | P56704 | 3/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066039 | 1.00 | TSHR (0.50) | TSHRITGB2ICAM1ITGALLMNA | |
| SCHEMBL27493 | 0.98 | TSHR (0.52) | TSHRITGB2ICAM1ITGALLMNA | |
| SCHEMBL16340888 | 0.98 | TSHR (0.52) | TSHRITGB2ICAM1ITGALLMNA | |
| SCHEMBL8447 | 0.91 | ITGB2 (0.52) | TSHRITGB2ICAM1ITGALLMNA | |
| Fluoride SCHEMBL28202465 | 0.91 | ITGB2 (0.52) | TSHRITGB2ICAM1ITGALLMNA | |
| SCHEMBL28007596 | 0.91 | ITGB2 (0.52) | TSHRITGB2ICAM1ITGALLMNA | |
| SCHEMBL5313090 | 0.91 | ITGB2 (0.52) | TSHRITGB2ICAM1ITGALLMNA | |
| SCHEMBL29356442 | 0.91 | ITGB2 (0.52) | TSHRITGB2ICAM1ITGALLMNA | |
| Ammonia Solution, Strong SCHEMBL2078097 | 0.89 | ITGB2 (0.50) | TSHRITGB2ICAM1ITGALLMNA | |
| Bromide SCHEMBL11373619 | 0.89 | ITGB2 (0.50) | TSHRITGB2ICAM1ITGALLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901787-B1 | Stabilized pharmaceutical composition | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0952826-B1 | IDEBENONE CONTAINING COMBINATION AGENT FOR TREATING ALZHEIMER'S DISEASE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6187340-B1 | TABLETS WITH COATINGS THAT PROTECT FROM LIGHT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0952826-A1 | IDEBENONE CONTAINING COMBINATION AGENT FOR TREATING ALZHEIMER'S DISEASE | Takeda Chemical Industries, Ltd. (JP) | 1999-11-03 | — | — | EP | disclosed |
| US-5962535-A | SYNERGISTIC MIXTURE OF IDEBENONE AND ACETYLCHOLINESTERASE INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0901787-A1 | Stabilized pharmaceutical composition | Takeda Chemical Industries, Ltd. (JP) | 1999-03-17 | — | — | EP | disclosed |
| WO-1998031356-A1 | IDEBENONE CONTAINING COMBINATION AGENT FOR TREATING ALZHEIMER'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-07-23 | — | — | WO | disclosed |
| EP-0487071-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-07-05 | — | — | EP | disclosed |
| US-5273974-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0487071-A1 | Condensed heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |