Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772366 | 1.00 | TSHR (0.44) | TSHRCYP2D6CYP3A4CYP1A2MAPK1 | |
| SCHEMBL2772125 | 1.00 | TSHR (0.44) | TSHRCYP2D6CYP3A4CYP1A2MAPK1 | |
| SCHEMBL2773433 | 1.00 | TSHR (0.44) | TSHRCYP2D6CYP3A4CYP1A2MAPK1 | |
| SCHEMBL7060888 | 1.00 | TSHR (0.44) | TSHRCYP2D6CYP3A4CYP1A2MAPK1 | |
| SCHEMBL7971333 | 0.92 | TSHR (0.52) | TSHRCYP2D6CYP3A4CYP1A2MAPK1 | |
| SCHEMBL2774395 | 0.92 | TSHR (0.52) | TSHRCYP2D6CYP3A4CYP1A2MAPK1 | |
| SCHEMBL7973573 | 0.92 | TSHR (0.52) | TSHRCYP2D6CYP3A4CYP1A2MAPK1 | |
| SCHEMBL7969980 | 0.92 | TSHR (0.52) | TSHRCYP2D6CYP3A4CYP1A2MAPK1 | |
| SCHEMBL2770246 | 0.92 | TSHR (0.52) | TSHRCYP2D6CYP3A4CYP1A2MAPK1 | |
| SCHEMBL7969847 | 0.92 | TSHR (0.52) | TSHRCYP2D6CYP3A4CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |