Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973573 | 1.00 | TSHR (0.52) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7969847 | 1.00 | TSHR (0.52) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7971333 | 1.00 | TSHR (0.52) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2774395 | 1.00 | TSHR (0.52) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2770246 | 1.00 | TSHR (0.52) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7960174 | 0.96 | TSHR (0.51) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7969868 | 0.96 | TSHR (0.51) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7959764 | 0.96 | TSHR (0.51) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7973175 | 0.96 | TSHR (0.51) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7969866 | 0.96 | TSHR (0.51) | TSHRALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |