Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063322 | 0.94 | TSHR (0.35) | TSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL7199625 | 0.90 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL7063329 | 0.81 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL7064537 | 0.80 | ALDH1A1 (0.37) | TSHRALDH1A1 | |
| SCHEMBL3132337 | 0.78 | ALDH1A1 (0.42) | TSHRALDH1A1 | |
| SCHEMBL3132355 | 0.78 | ALDH1A1 (0.42) | TSHRALDH1A1 | |
| SCHEMBL9617553 | 0.77 | GAA (0.36) | TSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL13415386 | 0.76 | TSHR (0.45) | TSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL8429717 | 0.76 | ALDH1A1 (0.43) | TSHRALDH1A1 | |
| SCHEMBL6915019 | 0.76 | ALDH1A1 (0.39) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6607631-B1 | Polymerizable monomer adhesive composition includes a 1,1-disubstituted ethylene monomer and at least one slip additive, where the slip additive causes a polymer film formed from the monomer to have a lower coefficient of friction than in an | CLOSURE MEDICAL CORPORATION | 2003-08-19 | — | — | US | claimed |
| WO-2002020684-A2 | ADHESIVE COMPOSITIONS WITH REDUCED COEFFICIENT OF FRICTION | CLOSURE MEDICAL CORPORATION (US) | 2002-03-14 | — | — | WO | claimed |
| US-6607631-B1 | Polymerizable monomer adhesive composition includes a 1,1-disubstituted ethylene monomer and at least one slip additive, where the slip additive causes a polymer film formed from the monomer to have a lower coefficient of friction than in an | CLOSURE MEDICAL CORPORATION | 2003-08-19 | — | — | US | disclosed |
| WO-2002020684-A2 | ADHESIVE COMPOSITIONS WITH REDUCED COEFFICIENT OF FRICTION | CLOSURE MEDICAL CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |