Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 19/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067996 | 1.00 | MMP1 (0.85) | MMP1 | |
| SCHEMBL7989123 | 0.93 | MMP1 (0.84) | MMP1 | |
| SCHEMBL7989118 | 0.93 | MMP1 (0.84) | MMP1 | |
| SCHEMBL7985530 | 0.92 | MMP1 (1.00) | MMP1 | |
| SCHEMBL7981507 | 0.92 | MMP1 (0.78) | MMP1 | |
| SCHEMBL7981510 | 0.92 | MMP1 (0.78) | MMP1 | |
| SCHEMBL7985753 | 0.91 | MMP1 (0.70) | MMP1 | |
| SCHEMBL7064618 | 0.91 | MMP1 (0.70) | MMP1 | |
| SCHEMBL7362840 | 0.91 | MMP1 (0.70) | MMP1 | |
| SCHEMBL7985711 | 0.90 | MMP1 (1.00) | MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966439-B1 | CERTAIN CYCLIC THIO SUBSTITUTED ACYLAMINOACID AMIDE DERIVATIVES | NOVARTIS AG (CH) | 2003-06-04 | — | — | EP | claimed |
| US-6034136-A | METALLOPROTEINASE INHIBITOR | NOVARTIS AG (CH) | 2000-03-07 | — | — | US | claimed |
| EP-0966439-B1 | CERTAIN CYCLIC THIO SUBSTITUTED ACYLAMINOACID AMIDE DERIVATIVES | NOVARTIS AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| US-6201133-B1 | FOR INHIBITING MATRIX-DEGRADING METALLOPROTEINASES IN MAMMALS, TREATING TNF ALPHA AND MATRIX METALLOPROTEINASE DEPENDENT DISEASES OR CONDITIONS, CANCER | NOVARTIS AG (CH) | 2001-03-13 | — | — | US | disclosed |