Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 4/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919304 | 0.71 | ALDH1A1 (0.40) | LMNANPC1RAB9ATDP1HPGD | |
| SCHEMBL6817904 | 0.69 | NPC1 (0.32) | LMNANPC1RAB9ATDP1HPGD | |
| SCHEMBL6919428 | 0.66 | NPC1 (0.39) | LMNANPC1RAB9ATDP1HPGD | |
| SCHEMBL7650689 | 0.66 | HPGD (0.52) | LMNANPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL6817908 | 0.65 | NPC1 (0.33) | LMNANPC1RAB9ATDP1HPGD | |
| SCHEMBL10730079 | 0.65 | ALDH1A1 (0.46) | LMNANPC1RAB9ATDP1HPGD | |
| SCHEMBL14220734 | 0.64 | ALDH1A1 (0.61) | LMNARAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL771475 | 0.64 | — | — | |
| SCHEMBL8560209 | 0.63 | DPP7 (0.40) | LMNANPC1RAB9ATDP1HPGD | |
| SCHEMBL28353718 | 0.63 | DPP7 (0.46) | LMNANPC1RAB9ATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |