SCHEMBL7064701

SCHEMBL7064701

CCOCCOCCOC(F)=C(F)F

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
THRB P10828 1/20 0.42
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5989763 0.98 ALDH1A1 (0.50) ALDH1A1TSHRTHRBMEN1POLB
SCHEMBL14992634 0.77
SCHEMBL7065420 0.76
SCHEMBL5028721 0.73
SCHEMBL5932668 0.73 ALDH1A1 (0.62) ALDH1A1TSHRTHRBMEN1POLB
SCHEMBL9639301 0.72 ALDH1A1 (0.56) ALDH1A1TSHRTHRBMEN1KMT2A
SCHEMBL989839 0.72 ALDH1A1 (0.56) ALDH1A1TSHRTHRBMEN1KMT2A
SCHEMBL987828 0.72 ALDH1A1 (0.56) ALDH1A1TSHRTHRBMEN1KMT2A
SCHEMBL5839297 0.72 ALDH1A1 (0.56) ALDH1A1TSHRTHRBMEN1KMT2A
SCHEMBL1204192 0.72 ALDH1A1 (0.56) ALDH1A1TSHRTHRBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030109653-A1 New fluoromonomers and methods of production, and new fluoropolymers produced therefrom SHOICHET MOLLY S (CA) 2003-06-12 US claimed
US-20030040591-A1 NEW FLUOROMONOMERS AND METHODS OF PRODUCTION, AND NEW FLUOROPOLYMERS PRODUCED THEREFROM SHOICHET MOLLY S (CA) 2003-02-27 US claimed
US-20030109653-A1 New fluoromonomers and methods of production, and new fluoropolymers produced therefrom SHOICHET MOLLY S (CA) 2003-06-12 US disclosed
US-6531558-B1 Such as 1-alkoxy/aryloxy-1,2,2-trifluoroethene which exhibits low protein absorption SHOICHET MOLLY S (CA) 2003-03-11 US disclosed
US-20030040591-A1 NEW FLUOROMONOMERS AND METHODS OF PRODUCTION, AND NEW FLUOROPOLYMERS PRODUCED THEREFROM SHOICHET MOLLY S (CA) 2003-02-27 US disclosed