⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45106 | 0.93 | — | — | |
| SCHEMBL4620757 | 0.93 | — | — | |
| SCHEMBL22635959 | 0.93 | — | — | |
| SCHEMBL2810989 | 0.92 | — | — | |
| SCHEMBL29406614 | 0.92 | — | — | |
| SCHEMBL15940395 | 0.88 | — | — | |
| SCHEMBL16448969 | 0.86 | — | — | |
| SCHEMBL1422833 | 0.85 | — | — | |
| SCHEMBL17735697 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL18344257 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669237-B2 | Biodegradable immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2014-03-11 | — | — | US | disclosed |
| US-20120121622-A1 | BIODEGRADABLE IMMUNOMODULATORY FORMULATIONS AND METHODS FOR USE THEREOF | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2012-05-17 | — | — | US | disclosed |
| US-8124590-B2 | Biodegradable immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110038896-A1 | Biodegradable immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2011-02-17 | — | — | US | disclosed |
| EP-1261378-B1 | BIODEGRADABLE IMMUNOMODULATORY FORMULATIONS AND METHODS FOR USE THEREOF | DYNAVAX TECH CORP (US) | 2010-03-10 | — | — | EP | disclosed |
| EP-1261377-B1 | IMMUNOMODULATORY FORMULATIONS AND METHODS FOR USE THEREOF | DYNAVAX TECH CORP (US) | 2009-09-02 | — | — | EP | disclosed |
| EP-2067487-A2 | Immunomodulatory formulations and methods for use thereof | Dynavax Technologies Corporation (US) | 2009-06-10 | — | — | EP | disclosed |
| US-20070258994-A1 | Immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION | 2007-11-08 | — | — | US | disclosed |
| US-7250403-B2 | Biodegradable immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2007-07-31 | — | — | US | disclosed |
| US-7183111-B2 | Immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2007-02-27 | — | — | US | disclosed |
| US-7129222-B2 | Immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2006-10-31 | — | — | US | disclosed |
| US-20030129251-A1 | Biodegradable immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION | 2003-07-10 | — | — | US | disclosed |
| US-20030059773-A1 | Immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION | 2003-03-27 | — | — | US | disclosed |
| US-20030022852-A1 | Biodegradable immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION | 2003-01-30 | — | — | US | disclosed |
| EP-1261377-A2 | IMMUNOMODULATORY FORMULATIONS AND METHODS FOR USE THEREOF | Dynavax Technologies Corporation (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-1261378-A2 | BIODEGRADABLE IMMUNOMODULATORY FORMULATIONS AND METHODS FOR USE THEREOF | Dynavax Technologies Corporation (US) | 2002-12-04 | — | — | EP | disclosed |
| US-20020055477-A1 | Immunomodulatory formulations and methods for use thereof | DYNAVAX TECHNOLOGIES CORPORATION | 2002-05-09 | — | — | US | disclosed |
| WO-2001068144-A2 | BIODEGRADABLE IMMUNOMODULATORY FORMULATIONS AND METHODS FOR USE THEREOF | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2001-09-20 | — | — | WO | disclosed |
| WO-2001068143-A2 | IMMUNOMODULATORY FORMULATIONS AND METHODS FOR USE THEREOF | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2001-09-20 | — | — | WO | disclosed |