SCHEMBL7064983

SCHEMBL7064983

CCCc1cc(F)c2c(c1)CC([C@H]1CC[C@H](CCC)CC1)C2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FYN P06241 1/20 0.33
TLR4 O00206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7651636 0.90 S1PR3 (0.33)
SCHEMBL4642771 0.80 FYN (0.35) FYNTLR4
SCHEMBL4645247 0.80 FYN (0.35) FYNTLR4
SCHEMBL4642780 0.80 FYN (0.35) FYNTLR4
SCHEMBL4645255 0.80 FYN (0.35) FYNTLR4
SCHEMBL4642776 0.80 FYN (0.35) FYNTLR4
SCHEMBL9391213 0.78 FYN (0.44) FYNTLR4
SCHEMBL9391219 0.78 FYN (0.44) FYNTLR4
SCHEMBL9391704 0.78 FYN (0.44) FYNTLR4
SCHEMBL9391697 0.78 FYN (0.44) FYNTLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1027403-B1 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME AVENTIS RES & TECH GMBH & CO (DE) 2003-05-28 EP disclosed
US-6485797-B1 5-Arylindane derivatives and ferroelectric liquid crystal mixture containing same AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 2002-11-26 US disclosed
EP-1027403-A2 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME Aventis Research & Technologies GmbH & Co. KG (DE) 2000-08-16 EP disclosed
WO-1999019420-A2 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-22 WO disclosed