Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 9/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506653 | 0.91 | CCR8 (0.70) | CCR8KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL7063399 | 0.91 | CCR8 (0.83) | CCR8KCNH2 | |
| SCHEMBL6509206 | 0.89 | CCR8 (0.64) | CCR8KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL6507972 | 0.89 | CCR8 (0.63) | CCR8KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL6501070 | 0.89 | CCR8 (0.86) | CCR8KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL7064954 | 0.89 | CCR8 (0.70) | CCR8KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL6496931 | 0.87 | CCR8 (0.53) | CCR8KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL6496975 | 0.83 | CCR8 (0.57) | CCR8KDM4EALDH1A1TDP1KCNH2 | |
| SCHEMBL6501296 | 0.81 | CCR8 (0.86) | CCR8KCNH2 | |
| SCHEMBL6509148 | 0.81 | CCR8 (1.00) | CCR8KCNH2HTTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |