Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2713588 | 0.84 | PRCP (0.51) | PRCPTLR2DPP7NOS2NOS3 | |
| SCHEMBL2638667 | 0.84 | PRCP (0.51) | PRCPTLR2DPP7NOS2NOS3 | |
| SCHEMBL8257937 | 0.84 | PRCP (0.51) | PRCPTLR2DPP7NOS2NOS3 | |
| Hydrochloric Acid SCHEMBL7370055 | 0.83 | PRCP (0.50) | PRCPTLR2DPP7NOS2 | |
| Hydrochloric Acid SCHEMBL7366846 | 0.83 | PRCP (0.50) | PRCPTLR2DPP7NOS2 | |
| SCHEMBL629326 | 0.80 | PRCP (0.54) | PRCPTLR2DPP7GAAMAPK1 | |
| SCHEMBL4916259 | 0.80 | PRCP (0.47) | PRCPTLR2DPP7 | |
| SCHEMBL14794763 | 0.80 | PRCP (0.47) | PRCPTLR2DPP7 | |
| SCHEMBL629327 | 0.80 | PRCP (0.54) | PRCPTLR2DPP7GAAMAPK1 | |
| SCHEMBL17560401 | 0.79 | NOS2 (0.44) | PRCPTLR2DPP7NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037346-A1 | 6-PHENYL-N-PHENYL-(1,3,5) -TRIAZINE-2,4-DIAMINE DERIVATIVES AND RELATED COMPOUNDS WITH LYSOPHPHOSPHATIDIC ACID ACYLTRANSFERASE BETA (LPAAT-BETA) INHIBITORY ACTIVITY FOR USE IN THE TREATMENT OF CANCER | CELL THERAPEUTICS, INC. (US) | 2003-05-08 | — | — | WO | disclosed |