SCHEMBL70654

SCHEMBL70654

O=C(O)c1cc(C(=O)O)c2ccccc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.65
NR4A1 P22736 1/20 0.59
NR4A2 P43354 1/20 0.59
NR4A3 Q92570 1/20 0.59
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
KDM4E B2RXH2 3/20 0.53
HSD17B10 Q99714 2/20 0.53
ALDH1A1 P00352 1/20 0.53
CYP1A2 P05177 1/20 0.53
GLA P06280 1/20 0.53
HPGD P15428 1/20 0.53
CYP2C19 P33261 1/20 0.53
CDC25B P30305 3/20 0.53
RXFP1 Q9HBX9 1/20 0.53
GPR35 Q9HC97 2/20 0.50
WDR5 P61964 1/20 0.50
POLB P06746 1/20 0.50
LDHA P00338 1/20 0.48
PTGER4 P35408 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406969 1.00 PTPN1 (0.65) PTPN1NR4A1NR4A2NR4A3MEN1
Hydrochloric Acid SCHEMBL17667161 0.98 PTPN1 (0.62) PTPN1NR4A1NR4A2NR4A3MEN1
SCHEMBL1878835 0.98 PTPN1 (0.62) PTPN1NR4A1NR4A2NR4A3MEN1
Hydrochloric Acid SCHEMBL10337056 0.98 PTPN1 (0.62) PTPN1NR4A1NR4A2NR4A3MEN1
Water SCHEMBL3833109 0.98 PTPN1 (0.62) PTPN1NR4A1NR4A2NR4A3MEN1
Water SCHEMBL28074781 0.96 PTPN1 (0.61) PTPN1NR4A1NR4A2NR4A3MEN1
SCHEMBL7542011 0.88 PTPN1 (0.60) PTPN1NR4A1NR4A2NR4A3MEN1
Phenylhydrazine SCHEMBL7536464 0.87 PTPN1 (0.51) PTPN1NR4A1NR4A2NR4A3MEN1
SCHEMBL9714537 0.86 PTPN1 (0.62) PTPN1NR4A1NR4A2NR4A3MEN1
SCHEMBL1355689 0.85 PTPN1 (0.51) PTPN1NR4A1NR4A2NR4A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2003 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024160205-A1 COLORED NYLON AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 中国石油化工股份有限公司 2024-08-08 WO claimed
CN-113066972-B Lithium-supplementing silicon material, preparation method thereof, electrode containing lithium-supplementing silicon material and battery 厦门高容新能源科技有限公司 2022-06-17 CN claimed
CN-113066972-A Lithium-supplementing silicon material, preparation method thereof, electrode containing lithium-supplementing silicon material and battery 厦门高容新能源科技有限公司 2021-07-02 CN claimed
US-10858747-B2 Acidic zinc and zinc nickel alloy plating bath composition and electroplating method ATOTECH DEUTSCHLAND GMBH (DE) 2020-12-08 US claimed
EP-3031861-B1 POLYESTER RESIN COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-01-08 EP claimed
CN-106661750-B Acidic zinc and Zinc-nickel alloy electroplating bath composition and electro-plating method 安美特德国有限公司 2019-01-29 CN claimed
CN-109134831-A A kind of copolyesters preparation method of high yield 广东舜天新材料有限公司 2019-01-04 CN claimed
US-9994382-B2 Oxygen-absorbing medical multilayer container and method for storing biological medicine MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-06-12 US claimed
EP-3015571-B1 Acidic zinc and zinc-nickel alloy plating bath composition and electroplating method ATOTECH DEUTSCHLAND GMBH (DE) 2018-05-02 EP claimed
US-9902852-B2 Polyester resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-02-27 US claimed
US-20020192172-A1 Emulsions with naphthalate esters COLGATE-PALMOLIVE COMPANY 2002-12-19 US claimed
US-6468511-B1 ANHYDROUS COSMETIC COMPRISING A NAPHTHALATE ESTER, A VOLATILE SILICONE BASED EMULSIFIER, A VOLATILE SILICONE AND ACTIVE INGREDIENT SUCH AS ANTIPERSPIRANT IN GLYCOL; EFFICIENT, STABLE COLGATE-PALMOLIVE COMPANY 2002-10-22 US claimed
WO-2001089465-A2 EMULSIONS WITH NAPHTHALATE ESTERS COLGATE-PALMOLIVE COMPANY (US) 2001-11-29 WO claimed
WO-1998042790-A1 CHEMICAL-MECHANICAL POLISHING SLURRY FORMULATION AND METHOD FOR TUNGSTEN AND TITANIUM THIN FILMS ADVANCED MICRO DEVICES, INC. (US) 1998-10-01 WO claimed
US-5607757-A Paper machine fabric EASTMAN CHEMICAL COMPANY (US) 1997-03-04 US claimed
US-5338881-A Process for preparing diketones EASTMAN CHEMICAL COMPANY (US) 1994-08-16 US claimed
EP-0540653-A1 PROCESS FOR PREPARING DIKETONES AND KETO-ACIDS EASTMAN KODAK COMPANY (US) 1993-05-12 EP claimed
US-5107029-A PROCESS FOR PREPARING DIKETONES AND KETO-ACIDS EASTMAN KODAK COMPANY (US) 1992-04-21 US claimed
WO-1992001662-A1 PROCESS FOR PREPARING DIKETONES AND KETO-ACIDS EASTMAN KODAK COMPANY (US) 1992-02-06 WO claimed
US-4447593-A HIGH STRENGTH; MELT-SHAPEABLE; TEIJIN LIMITED (JP) 1984-05-08 US claimed