SCHEMBL7542011

SCHEMBL7542011

O=C(O)c1ccc(C(=O)c2cc(C(=O)O)c3ccccc3c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.60
SRD5A2 P31213 4/20 0.55
KDM4E B2RXH2 2/20 0.53
CDC25B P30305 4/20 0.50
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
CYP2C8 P10632 1/20 0.49
CYP2C9 P11712 1/20 0.49
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
RXFP1 Q9HBX9 1/20 0.46
CDC25A P30304 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP1A2 P05177 1/20 0.46
GLA P06280 1/20 0.46
HPGD P15428 1/20 0.46
CYP2C19 P33261 1/20 0.46
POLB P06746 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7537964 0.90 POLB (0.58) PTPN1SRD5A2KDM4ECDC25BNR4A1
SCHEMBL29406969 0.88 PTPN1 (0.65) PTPN1KDM4ECDC25BNR4A1NR4A2
SCHEMBL70654 0.88 PTPN1 (0.65) PTPN1KDM4ECDC25BNR4A1NR4A2
SCHEMBL7536398 0.86 PTPN1 (0.49) PTPN1SRD5A2KDM4ECDC25BNR4A1
Water SCHEMBL3833109 0.86 PTPN1 (0.62) PTPN1KDM4ECDC25BNR4A1NR4A2
SCHEMBL1878835 0.86 PTPN1 (0.62) PTPN1KDM4ECDC25BNR4A1NR4A2
Hydrochloric Acid SCHEMBL17667161 0.86 PTPN1 (0.62) PTPN1KDM4ECDC25BNR4A1NR4A2
Hydrochloric Acid SCHEMBL10337056 0.86 PTPN1 (0.62) PTPN1KDM4ECDC25BNR4A1NR4A2
Water SCHEMBL28074781 0.84 PTPN1 (0.61) PTPN1KDM4ECDC25BNR4A1NR4A2
SCHEMBL9714537 0.78 PTPN1 (0.62) PTPN1KDM4ECDC25BNR4A1NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 PTPN1 2904/4885SRD5A2 4141/4885KDM4E 3406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.