Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 17/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 16/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 16/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316116 | 0.87 | ITGAL (0.46) | ITGALITGB2ICAM1NPSR1 | |
| SCHEMBL6919945 | 0.85 | ITGAL (0.48) | ITGALITGB2ICAM1NPSR1MEN1 | |
| SCHEMBL7065475 | 0.84 | ITGB2 (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL6310230 | 0.81 | ITGB2 (0.44) | ITGALITGB2ICAM1MEN1KMT2A | |
| SCHEMBL6197120 | 0.76 | ITGAL (0.47) | ITGALITGB2ICAM1MEN1KMT2A | |
| SCHEMBL6194905 | 0.76 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL6312268 | 0.75 | ITGB2 (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL6198270 | 0.74 | ITGAL (0.66) | ITGALITGB2ICAM1NPSR1KMT2A | |
| SCHEMBL6312033 | 0.73 | ITGB2 (0.51) | ITGALITGB2ICAM1 | |
| SCHEMBL6312040 | 0.72 | ITGAL (0.47) | ITGALITGB2ICAM1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |