Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 7/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.48 |
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312040 | 0.86 | ITGAL (0.47) | ITGALITGB2ICAM1THRBNPSR1 | |
| SCHEMBL7065452 | 0.85 | ITGAL (0.51) | ITGALITGB2ICAM1NPSR1KMT2A | |
| SCHEMBL6310206 | 0.84 | ITGAL (0.45) | ITGALITGB2ICAM1THRBNPSR1 | |
| SCHEMBL6530924 | 0.83 | THRB (0.43) | ITGALITGB2ICAM1THRBNPSR1 | |
| SCHEMBL7641650 | 0.82 | ITGAL (0.43) | ITGALITGB2ICAM1THRBKMT2A | |
| SCHEMBL6309661 | 0.80 | MGLL (0.44) | ITGALITGB2ICAM1KMT2AMEN1 | |
| SCHEMBL6317717 | 0.80 | ITGAL (0.43) | ITGALITGB2ICAM1KMT2AMEN1 | |
| SCHEMBL6317025 | 0.80 | ITGAL (0.43) | ITGALITGB2ICAM1KMT2AMEN1 | |
| SCHEMBL6917200 | 0.79 | ITGAL (0.42) | ITGALITGB2ICAM1THRBKMT2A | |
| SCHEMBL6199026 | 0.78 | ITGAL (0.52) | ITGALITGB2ICAM1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |