Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 18/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.51 |
| ▸ | ITGAL | P20701 | 18/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530920 | 0.86 | RAB9A (0.49) | ITGB2ICAM1ITGALNPC1RAB9A | |
| SCHEMBL7065447 | 0.85 | ITGB2 (0.53) | ITGB2ICAM1ITGAL | |
| SCHEMBL6312029 | 0.83 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL6917194 | 0.82 | RAB9A (0.52) | ITGB2ICAM1ITGALNPC1RAB9A | |
| SCHEMBL6405996 | 0.76 | ITGB2 (0.52) | ITGB2ICAM1ITGAL | |
| SCHEMBL6310228 | 0.76 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL6311223 | 0.74 | ITGB2 (0.48) | ITGB2ICAM1ITGAL | |
| SCHEMBL6308901 | 0.74 | ITGB2 (0.48) | ITGB2ICAM1ITGAL | |
| SCHEMBL6310845 | 0.74 | ITGB2 (0.48) | ITGB2ICAM1ITGAL | |
| SCHEMBL6919943 | 0.71 | ITGAL (0.52) | ITGB2ICAM1ITGALNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |