Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | LMNA | P02545 | 8/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 11/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065013 | 0.95 | ALDH1A1 (0.39) | ALDH1A1LMNATDP1MAPTMEN1 | |
| SCHEMBL7064848 | 0.93 | ALDH1A1 (0.39) | ALDH1A1LMNATDP1MAPTMEN1 | |
| SCHEMBL7066729 | 0.85 | ALDH1A1 (0.53) | ALDH1A1LMNATDP1MAPTMEN1 | |
| SCHEMBL7065975 | 0.84 | MAPT (0.39) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7065007 | 0.83 | MAPT (0.43) | ALDH1A1LMNATDP1MAPTMEN1 | |
| SCHEMBL7066074 | 0.83 | MAPT (0.36) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7065574 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNATDP1MAPTMEN1 | |
| SCHEMBL7066010 | 0.81 | GRIN2D (0.41) | ALDH1A1LMNATDP1MAPTMEN1 | |
| SCHEMBL7065572 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNATDP1MAPTMEN1 | |
| SCHEMBL7062996 | 0.81 | MAPT (0.38) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313461-A2 | THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | Melacure Therapeutics AB (SE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002011715-A2 | THE USE OF BENZYLIDENEAMINOGUANIDINES AND HYDROXYGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS | MELACURE THERAPEUTICS AB (SE) | 2002-02-14 | — | — | WO | disclosed |