Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384694 | 0.79 | TSHR (0.41) | SMN1; SMN2GAAKMT2ATSHRHPGD | |
| SCHEMBL9099802 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2GAAKMT2AFFAR1TSHR | |
| SCHEMBL5971439 | 0.76 | HPGD (0.49) | GAAKMT2ATSHRHPGDL3MBTL1 | |
| SCHEMBL30394799 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKMT2AFFAR1TSHR | |
| SCHEMBL1515738 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKMT2AFFAR1TSHR | |
| SCHEMBL1533397 | 0.72 | CES1 (0.48) | GAAKMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL1824047 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2GAAKMT2AFFAR1TSHR | |
| SCHEMBL10823798 | 0.69 | CES1 (0.50) | GAAKMT2ATSHRMAPK1L3MBTL1 | |
| SCHEMBL66063 | 0.69 | CES1 (0.50) | KMT2ATSHRMAPK1L3MBTL1CES2 | |
| Phenylacetic Acid SCHEMBL28136536 | 0.68 | AKR1B1 (0.77) | SMN1; SMN2GAAFFAR1TSHRTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313718-A2 | INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES | Biotie Therapies Corp. (FI) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002002090-A2 | INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES | BIOTIE THERAPIES CORP. (FI) | 2002-01-10 | — | — | WO | disclosed |