SCHEMBL66063

SCHEMBL66063

C[C](Cl)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.50
CES2 O00748 1/20 0.50
AKR1B1 P15121 1/20 0.50
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
TSHR P16473 2/20 0.43
TP53 P04637 1/20 0.43
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
MAPT P10636 1/20 0.42
NOS2 P35228 1/20 0.41
CALM1 P0DP23 1/20 0.41
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575184 0.83 CES1 (0.55) CES1CES2AKR1B1FNTAFNTB
SCHEMBL28779184 0.80 CES1 (0.46) CES1CES2AKR1B1FNTAFNTB
SCHEMBL27992720 0.79 CES1 (0.50) CES1CES2AKR1B1FNTAFNTB
SCHEMBL66721 0.78 CES1 (0.55) CES1CES2AKR1B1FNTAFNTB
SCHEMBL2792481 0.78 CES1 (0.55) CES1CES2AKR1B1FNTAFNTB
SCHEMBL57392 0.78 CES1 (0.55) CES1CES2AKR1B1FNTAFNTB
SCHEMBL15301721 0.77 CES1 (0.43) CES1CES2AKR1B1FNTAFNTB
SCHEMBL8522659 0.77 CES1 (0.43) CES1CES2AKR1B1FNTAFNTB
SCHEMBL28774551 0.76 CES1 (0.52) CES1CES2AKR1B1FNTAFNTB
SCHEMBL9317795 0.76 CES1 (0.52) CES1CES2AKR1B1FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107075121-B Polysiloxane copolymers or terpolymers and polymers made therefrom 莫门蒂夫性能材料股份有限公司 2021-01-22 CN claimed
US-9812661-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2017-11-07 US claimed
US-9716235-B2 9,10-bis[2-(p-substituted phenyl)pyrimidin-4-yl] anthracene compounds, methods of preparing the same, organic electroluminescent devices and organic electroluminescent display apparatus BOE TECHNOLOGY GROUP CO., LTD. (CN) 2017-07-25 US claimed
US-20150214487-A1 9,10-Bis[2-(p-substituted phenyl)pyrimidin-4-yl] Anthracene Compounds, Methods of Preparing the Same, Organic Electroluminescent Devices and Organic Electroluminescent Display Apparatus BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-07-30 US claimed
EP-2314558-B1 BENZOFLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT COMPRISING SAME IDEMITSU KOSAN CO (JP) 2014-05-14 EP claimed
US-8101290-B2 Organic compound having electron-transporting and/or hole-blocking performance and its use and OLEDs comprising the compound TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) 2012-01-24 US claimed
US-8084177-B2 Toners containing polyhedral oligomeric silsesquioxanes XEROX CORPORATION (US) 2011-12-27 US claimed
US-7985523-B2 Toners containing polyhedral oligomeric silsesquioxanes XEROX CORPORATION (US) 2011-07-26 US claimed
US-20110034733-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2011-02-10 US claimed
US-20100159375-A1 TONERS CONTAINING POLYHEDRAL OLIGOMERIC SILSESQUIOXANES XEROX CORPORATION (US) 2010-06-24 US claimed
US-20100159376-A1 TONERS CONTAINING POLYHEDRAL OLIGOMERIC SILSESQUIOXANES XEROX CORPORATION (US) 2010-06-24 US claimed
US-20090102356-A1 NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) 2009-04-23 US claimed
US-20090043116-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2009-02-12 US claimed
US-7144968-B2 Silicon-containing polymer, process for its production, resist composition employing it, pattern-forming method and electronic device fabrication method FUJITSU LIMITED (JP) 2006-12-05 US claimed
US-20050038216-A1 Silicon-containing polymer, process for its production, resist composition employing it, pattern-forming method and electronic device fabrication method FUJITSU LIMITED 2005-02-17 US claimed
US-6653365-B2 Polymerizable resin, a filler system comprising polyhedral polysilsesquioxane fillers, and a curing system; useful as crown and bridge materials, reconstructive or restorative materials PENTRON CLINICAL TECHNOLOGIES, LLC 2003-11-25 US claimed
US-6541077-B1 Negative non-chemical amplification resist polymer or a positive chemical amplification resist polymer FUJITSU LIMITED (JP) 2003-04-01 US claimed
US-20020198282-A1 Dental composite materials and method of manufacture thereof PENTRON CORPORATION 2002-12-26 US claimed
US-20020120058-A1 Silicon-containing polymer, process for its production, resist composition employing it, pattern-forming method and electronic device fabrication method FUJITSU LIMITED 2002-08-29 US claimed
US-6342562-B1 POLYSILICATE MODIFIED WITH ALKYLCARBOXY SILOXANE; AMPLIFICATION; PHOTORESIST FUJITSU LIMITED (JP) 2002-01-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034733-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, DDC, EML4 CES1 4681/4885CES2 1668/4885AKR1B1 3524/4885
US-20090102356-A1 NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND SLCO4C1, SLCO1B1, SLCO2B1 CES1 4331/4885CES2 3677/4885AKR1B1 2274/4885
US-20090043116-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS PBRM1, BICRA, PARG CES1 4657/4885CES2 3527/4885AKR1B1 4635/4885
US-20150214487-A1 9,10-Bis[2-(p-substituted phenyl)pyrimidin-4-yl] Anthracene Compounds, Methods of Preparing the Same, Organic Electroluminescent Devices and Organic Electroluminescent Display Apparatus P2RY10, P2RY4, APRT CES1 4540/4885CES2 3523/4885AKR1B1 1511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.